MicroRNA-103a-3p Promotes Cell Proliferation and Invasion in Non-Small-Cell Lung Cancer Cells through Akt Pathway by Targeting PTEN

Figure 3

siPTEN promotes the proliferation, invasion, and Akt signaling in NSCLC cells. Relative expression of PTEN mRNA (a) and protein (b) were detected by qRT-PCR and western blot after transfected with PTEN siRNA or NC siRNA for 48 h. (c) MTT assay on effect of PTEN knockdown. (d) Transwell invasion assay on effect of PTEN knockdown. Relative expression of p-Akt/Akt protein was detected by western blot after PTEN knockdown (e) or transfected with miR-103a-3p mimics/inhibitor (f) (, ).

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