Propranolol Suppresses Proliferation and Migration of HUVECs through Regulation of the miR-206/VEGFA Axis

Figure 3

Downregulation of miR-206 reverses propranolol-induced inhibition of cell migration in HUVECs. HUVECs were divided into three groups: control, 80 μM propranolol, 80 μM propranolol + miR-206 antagomir. (a) and (b) Representative scratching area of cells and the calculated wound healing rate were indicated. (c) and (d) Migrated cells were stained with 0.2% crystal violet and counted at 3 random fields. (e) Representative images of tube formation were captured by microscopy at 24 h. (f) and (g) Branch points counts and capillary length were calculated at 3 random fields. , comparing with the control group; ^##, comparing with the propranolol group; .

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