Development and Validation of an Autophagy-Related Gene Signature for Predicting the Prognosis of Hepatocellular Carcinoma

Table 3

Univariate and multivariate regression analyses of OS in HCC patients of the TCGA training group.

Variable	Univariate analysis			Multivariate analysis
		Hazard ratio	95% confidence interval		Hazard ratio	95% confidence interval
Age (≥60/<60)	0.220	1.378	0.826-2.301
Sex (female/male)	0.776	1.079	0.639-1.822
AJCC stage ()	0.007	2.061	1.216-3.494	0.042	1.745	1.021-2.983
Histologic grade ()	0.276	0.744	0.437-1.266
Risk score (high/low)	<0.001	4.027	2.410-6.728	<0.001	3.775	2.251-6.328

Notes: AJCC: American Joint Committee on Cancer; OS: overall survival; HCC: hepatocellular carcinoma; TCGA: The Cancer Genome Atlas.