Development and Validation of an Autophagy-Related Gene Signature for Predicting the Prognosis of Hepatocellular Carcinoma

Table 4

Univariate and multivariate regression analyses of OS in HCC patients of the TCGA testing group.

Variable	Univariate analysis			Multivariate analysis
		Hazard ratio	95% confidence interval		Hazard ratio	95% confidence interval
Age (≥60/<60)	0.808	1.071	0.616-1.863
Sex (female/male)	0.082	1.637	0.940-2.852
AJCC stage ()	<0.001	3.495	2.002-6.100	<0.001	3.545	2.017-6.231
Histologic grade ()	0.025	1.886	1.084-3.280	0.036	1.831	1.041-3.221
Risk score (high/low)	0.006	2.201	1.259-3.850	0.020	1.947	1.109-3.416

Notes: AJCC: American Joint Committee on Cancer; OS: overall survival; HCC: hepatocellular carcinoma; TCGA: The Cancer Genome Atlas.