Development and Validation of an Autophagy-Related Gene Signature for Predicting the Prognosis of Hepatocellular Carcinoma

Table 5

Univariate and multivariate regression analyses of OS in HCC patients of the ICGC dataset.

Variable	Univariate analysis			Multivariate analysis
	value	Hazard ratio	95% confidence interval	value	Hazard ratio	95% confidence interval
Age (≥60/<60)	0.590	0.823	0.405-1.671
Sex (female/male)	0.039	1.926	1.033-3.590	0.017	2.231	1.152-4.322
AJCC stage ()	0.005	2.384	1.304-4.359	0.002	2.726	1.437-5.173
Prior malignancy (yes/no)	0.180	1.750	0.773-3.963
Risk (high/low)	<0.001	4.528	2.462-8.328	<0.001	4.084	2.214-7.533

Notes: AJCC: American Joint Committee on Cancer; OS: overall survival; HCC: hepatocellular carcinoma; ICGC: International Cancer Genome Consortium.