Research Article
Development and Validation of an Autophagy-Related Gene Signature for Predicting the Prognosis of Hepatocellular Carcinoma
Table 7
Univariate and multivariate regression analyses of OS in HCC patients of the AHMU dataset.
| Variable | Univariate analysis | Multivariate analysis | value | Hazard ratio | 95% confidence interval | value | Hazard ratio | 95% confidence interval |
| Age (≥60/<60) | 0.908 | 0.962 | 0.497-1.861 | | | | Sex (female/male) | 0.664 | 0.841 | 0.385-1.839 | | | | AJCC stage () | 0.014 | 2.303 | 1.184-4.480 | — | | | Cirrhosis (yes/no) | 0.330 | 0.721 | 0.374-1.391 | | | | Tumor size (>5/≤5 cm) | 0.432 | 1.296 | 0.679-2.473 | | | | Tumor number (multiple/single) | 0.004 | 2.687 | 1.365-5.291 | 0.013 | 2.372 | 1.203-4.676 | Differentiation () | 0.471 | 1.265 | 0.667-2.398 | | | | Risk (high/low) | 0.005 | 2.752 | 1.358-5.575 | 0.011 | 2.517 | 1.238-5.119 |
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Notes: AJCC: American Joint Committee on Cancer; OS: overall survival; HCC: hepatocellular carcinoma.
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