Selected E2F2 Polymorphisms in Oral and Oropharyngeal Squamous Cell Carcinoma

Table 4

Associations of E2F2 genotypes with odds of OSCC and OPSCC patients and controls.

SNP ID	Genotypes	OSCC and OPSCC	Controls	value	OR (95% CI)
rs6667575	G/G	46	38	≤1	0.62 (0.35-1.11)
	A/G	36	53	≤0.1	1.79 (1.01-3.19)
	A/A	10	8	≤1	0.72 (0.27-1.91)
	Var. (A)	46	61	≤1	1.61 (0.90-2.85)
	Ref. (G)	82	91	≤1	1.39 (0.52-3.68)
rs3218121	G/G	80	0	—	Absent in control
	A/G	3	79	≤0.001	127.51 (36.38-446.93)
	A/A	12	19	≤1	1.66 (0.76-3.65)
	Var. (A)	15	98	—	G/G homozygote absent in control
	Ref. (G)	83	79	≤1	0.60 (0.27-1.32)
rs3218211	A/A	25	26	≤1	0.97 (0.51-1.84)
	G/A	40	50	≤1	1.35 (0.77-2.39)
	G/G	28	23	≤1	0.70 (0.37-1.34)
	Var. (G)	68	73	≤1	1.03 (0.54-1.96)
	Ref. (A)	65	76	≤1	1.42 (0.75-2.71)
rs3218148	G/G	15	17	≤1	1.11 (0.52-2.37)
	A/G	48	57	≤1	1.34 (0.75-2.37)
	A/A	30	23	≤1	0.65 (0.34-1.24)
	Var. (A)	78	80	≤1	0.90 (0.42-1.94)
	Ref. (G)	63	74	≤1	1.53 (0.81-2.90)
rs3218203	C/C	65	63	≤1	0.86 (0.47-1.56)
	G/C	30	32	≤1	1.07 (0.58-1.95)
	G/G	0	2	—	Absent in cancer
	Var. (G)	30	34	≤1	1.17 (0.64-2.13)
	Ref. (C)	95	95	—	G/G homozygote absent in cancer