Comprehensive Analysis of Glutamate-Rich WD Repeat-Containing Protein 1 and Its Potential Clinical Significance for Pancancer

Figure 5

Correlation between the expression level of GRWD1 and endothelial cells, infiltration of cancer-associated fibroblasts, and expression levels of immune checkpoint-related genes. (a, b) The EPIC, MCPcounter, xCell, and TIDE algorithms were used for the correlation analysis of the infiltration levels of cancer-related endothelial cells and fibroblasts and the expression level of GRWD1 in all types of cancer in TCGA. Red indicates a positive correlation (0–1), and blue shows a negative correlation (−1–0). value < 0.05 represents a statistically significant difference. Correlation values that are not statistically significant are marked with crosses. (c) Heat map indicates the expression levels of immune checkpoint-related genes in different tumor tissues; the horizontal axis represents different tumor tissues, the vertical axis shows the expression levels of immune checkpoint-related genes, blue indicates a positive correlation, and red represents a negative correlation. ; .

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