ZC3H15 Correlates with a Poor Prognosis and Tumor Progression in Melanoma

<div>ZC3H15 promotes cell proliferation in melanoma cells. (a) Western blot analyses of ZC3H15 in cells with ZC3H15-knockdown. (b) MTT assay was performed to examine the viability of ZC3H15- knockdown melanoma cells. (c) BrdU incorporation assays were performed to detect the amount of DNA synthesis in ZC3H15-knockdown melanoma cells. (d) After restoration of ZC3H15 in ZC3H15-knockdown cells, the expression of ZC3H15 at protein and mRNA level was detected using quantitative PCR assays and Western blot, respectively. (e) MTT assay was performed in ZC3H15-rescued cells. (f) BrdU was carried out after ZC3H15 was rescued in ZC3H15-knockdown cells. 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BioMed Research International

fig2

Figure 2

Figure 2: ZC3H15 Correlates with a Poor Prognosis and Tumor Progression in Melanoma 