ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway

<div>ADAM17 involvement in hypoxic-regulated keratinocyte migration. (a, e) The ADAM17 inhibitor TAPI-2 or si-ADAM17 effect on the wound closure in keratinocytes under hypoxic condition. (b, f) Quantification analysis of wound healing assays using ImageJ software. (c, g) The effect of ADAM17 inhibitor TAPI-2 or si-ADAM17 on cell motility trajectories in keratinocytes under hypoxic condition. (d, h) Statistical value of cell trajectory speed. 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27V0H384Z"></path></g></svg> vs the control group. Bar = 100 <i>μ</i> m.</div>

BioMed Research International

fig3

Figure 3

Figure 3: ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway 