Comprehensive Analysis of CD163 as a Prognostic Biomarker and Associated with Immune Infiltration in Glioblastoma Multiforme

<div>The prognosis analysis of differentially expressed genes in GBM in CGGA cohort. (a) Overall survival analysis of CD163 in GBM. (b) Overall survival analysis of CHI3L2 in GBM. (c, d) Hazard ratio and <svg height="10.2124pt" id="M31" style="vertical-align:-3.42943pt" version="1.1" viewbox="-0.0498162 -6.78297 7.83752 10.2124" width="7.83752pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M570 304C570 398 525 448 414 448C385 448 343 445 312 434L329 511L321 518C297 504 262 482 244 460L233 411C195 397 159 381 128 358L135 332C160 347 189 360 224 373L111 -147C97 -210 84 -218 17 -231L13 -257L254 -247L259 -218L233 -216C183 -212 177 -202 189 -142L218 -1C238 -10 266 -12 283 -12C351 3 429 48 483 105C543 168 570 242 570 304ZM482 289C482 161 380 33 304 33C278 33 248 51 233 69L303 396C326 400 352 403 369 403C428 403 482 380 482 289Z"></path></g></svg> value of constituents involved in univariate and multivariate Cox regressions considering clinical parameters and CD163 and CHI3L2. (e, f) Nomogram to predict the 1 y, 2 y, and 3 y overall survival of GBM patients. Calibration curve for the overall survival nomogram model in the discovery group. A dashed diagonal line represents the ideal nomogram, and the blue line, red line, and orange line represent the 1 y and 2 y observed nomograms.</div>

BioMed Research International

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Figure 6

Figure 6: Comprehensive Analysis of CD163 as a Prognostic Biomarker and Associated with Immune Infiltration in Glioblastoma Multiforme 