Comprehensive Analysis of CD163 as a Prognostic Biomarker and Associated with Immune Infiltration in Glioblastoma Multiforme

Table 2

Correlation analysis between CD163 and gene biomarkers of immune cells in GBM.

Immune cells	Gene markers	GBM
		TCGA		CGGA
		Cor	value	Cor	value
CD8+ T cell	CD8A	0.202		0.441
	CD8B	0.241		0.516
T cell (general)	CD3D	0.378		0.55
	CD3E	0.392		0.628
	CD2	0.422		0.624
B cell	CD19	0.097	0.231	0.321
	CD79A	0.187		0.32
Monocyte	CD86	0.58		0.673
	CD115 (CSF1R)	0.617		0.462
TAM	CCL2	0.567		0.652
	CD68	0.677		0.746
	IL10	0.593		0.662
M1 macrophage	INOS (NOS2)	-0.037	0.649	0.206
	IRF5	0.317		0.498
	COX2 (PTGS2)	0.558		0.447
M2 macrophage	VSIG4	0.798		0.735
	MS4A4A	0.835		0.851
Neutrophils	CD66b (CEACAM8)	0.002	0.977	—	—
	CD11b (ITGAM)	0.607		0.613
	CCR7	0.475		0.497
Natural killer cell	KIR2DL1	0.13	0.11	—	—
	KIR2DL3	0.009	0.911	—	—
	KIR2DL4	0.236		0.346
	KIR3DL1	0.021	0.799	—	—
	KIR3DL2	0.002	0.985	—	—
	KIR3DL3	0.105	0.195	—	—
	KIR2DS4	0.184	0.0228	—	—
Dendritic cell	HLA-DPB1	0.57		0.666
	HLA-DQB1	0.328		0.424
	HLA-DRA	0.573		0.736
	HLA-DPA1	0.467		0.687
	BDCA-1 (CD1C)	0.349		0.413
	BDCA-4 (NRP1)	0.585		0.763
	CD11c (ITGAX)	0.171		0.385
Th1	T-bet (TBX21)	0.031	0.707	0.233
	STAT4	0.318		0.017	0.794
	STAT1	-0.022	0.783	0.45
	IFN-g (IFNG)	0.134	0.0977	—	—
	TNF-a (TNF)	0.135	0.0967	0.126	0.0595
Th2	GATA3	0.277		0.273
	STAT6	0.442		0.651
	STAT5A	0.399		0.623
	IL13	-0.169		0.09	0.18
Tfh	BCL6	0.218		0.295
	IL21	-0.009	0.91	—	—
Th17	STAT3	0.248		0.681
	IL17A	-0.019	0.82	—	—
Treg	FOXP3	0.296		0.263
	CCR8	0.393		—	—
	STAT5B	-0.103	0.204	-0.079	0.238
	TGFb (TGFB1)	0.427		0.62
T cell exhaustion	PD-1 (PDCD1)	0.354		0.516
	CTLA4	0.429		0.362
	LAG3	0.023	0.777	0.37
	TIM-3 (HAVCR2)	0.442		0.622
	GZMB	0.332		0.565

, , . —: no data.