Research Article

[Retracted] SOCS3 Gene Polymorphism and Hypertension Susceptibility in Chinese Population: A Two-Center Case-Control Study

Table 2

Association between SOCS3 rs8064821 C>A polymorphism and hypertension risk in Guangxi Province.

ModelsGenotypesControl, (%)Hypertension, (%)Unadjusted OR (95% CI) valueAdjusted OR (95% CI)Adjusted value

rs8064821 C>A
AdditiveCC171 (61.3)127 (51.2)1.00 (reference)1.00 (reference)
CA98 (35.1)102 (41.1)1.401 (0.978-2.009)0.0662.647 (1.391-5.038)0.003
AA10 (3.6)19 (7.7)2.558 (1.150-5.690)0.0215.776 (1.613-20.682)0.007
DominantCC171 (61.3)127 (51.2)1.00 (reference)1.00 (reference)
CA/AA108 (38.7)121 (48.8)1.509 (1.067-2.133)0.0202.943 (1.584-5.466)0.001
RecessiveCC/CA269 (96.4)229 (92.3)1.00 (reference)1.00 (reference)
AA10 (3.6)19 (7.7)2.232 (1.017-4.897)0.0453.729 (1.119-12.426)0.032

OR: odds ratio; CI: confidence interval. Adjusted for age, gender, BMI, smoking history, FBG, and dyslipidemia.