Research Article

[Retracted] SOCS3 Gene Polymorphism and Hypertension Susceptibility in Chinese Population: A Two-Center Case-Control Study

Table 4

Association between SOCS3 rs8064821 C>A polymorphism and hypertension risk in combined subjects.

ModelsGenotypesControl, (%)Hypertension, (%)Unadjusted OR (95% CI) valueAdjusted OR (95% CI)Adjusted value

rs8064821 C>A
AdditiveCC358 (62.9)273 (52.3)1.00 (reference)1.00 (reference)
CA188 (33.0)212 (40.6)1.479 (1.150-1.902)0.0021.821 (1.276-2.600)0.001
AA23 (4.1)37 (7.1)2.110 (1.225-3.634)0.0072.143 (1.042-4.410)0.038
DominantCC358 (62.9)273 (52.3)1.00 (reference)1.00 (reference)
CA/AA211 (37.1)249 (47.7)1.548 (1.215-1.971)<0.0011.863 (1.326-2.619)<0.001
RecessiveCC/CA546 (95.9)485 (92.9)1.00 (reference)1.00 (reference)
AA23 (4.1)37 (7.1)1.811 (1.061-3.091)0.0291.696 (0.839-3.428)0.141

OR: odds ratio; CI: confidence interval. Adjusted for age, gender, BMI, smoking history, FBG, and dyslipidemia.