Mechanistic Investigation on the Regulation of FABP1 by the IL-6/miR-603 Signaling in the Pathogenesis of Hepatocellular Carcinoma

Figure 1

FABP1 expression in HCC and adjacent tissues. (a) Representative image of FABP1 staining by IHC in HCC tissue and the corresponding adjacent tissue array. The images of low-power field of view were magnified 100-fold, as shown in the left panel, , and the images in the boxes were magnified 400-fold, as shown in the right panel, . The FABP1-positive tissue was stained in brown. (b) FABP1 staining index in the tissue array. Data are expressed as the , for each group. . (c) FABP1 staining score in four clinical stages of HCC and adjacent tissues. Data are expressed as the , for T1, for T2, for T3, and for T4. , , and . (d) Survival curve generated by the Kaplan-Meier analysis in patients with high and low FABP1 expression (). (e) Representative image of fatty acid staining by Oil Red O staining in HCC tissue and the corresponding adjacent tissues. Images in the upper panel were magnified 100-fold, . The images in the boxes were magnified 400-fold, as shown in the bottom panel, .

(a)

(b)

(c)

(d)

(e)