Is Electroacupuncture an Effective and Safe Treatment for Poststroke Depression? An Updated Systematic Review and Meta-Analysis

Table 1

Main characteristics of included studies.

Study	Sample size	Diagnostic criteria of PSD	Baseline HAMD	Intervention	Control	No. of EA sessions	Treatment duration	Jadad score
Zhang and Yan [8]	E: 35; C: 35	CCMD/HAMD	E: C:	GV20, HT7, LR3; 30 min, once a day	20 mg/d paroxetine	28	4	2 (2, 0, 0, 0)
Xu and Miago [7]	E: 40; C: 40	CCCD/CCMD/HAMD	E: C:	GV20, EX-HN1, EX-HN3, LR3, HT7, PC6, KI3, SP6, BL15; 30 min, once a day	20 mg/d fluoxetine	42	6	1 (1, 0, 0, 0)
Wang et al. [6]	E: 25; E2: 25; E3: 25; C: 25	CCCD/CCMD/HAMD	E1: E2: E3: C:	GV20, GV24, PC6, HT7; 30 min, once a day	50 mg/d sertraline	30	4	2 (1, 1, 0, 0)
Li et al. [19]	E: 11; C: 10	CCCD/HAMD	E: C:	LI4, LR3; 20 min, once a day	20 mg/d fluoxetine	40	8	3 (2, 1, 0, 0)
Hong et al. [9]	E: 30; C: 30	CCCD/CCMD/HAMD	E: C:	GV20, EX-HN1, GV24, ST36, LR3, SP6; 30 min, once a day	20 mg/d citalopram	30	4	3 (2, 1, 0, 0)
Kang and Yang [20]	E: 40; C: 40	CCCD/CCMD/HAMD	E: C:	GV24, G13, GB31, SJ17, EX-HN3; 30 min, once a day	20 mg/d fluoxetine	28	4	1 (1, 0, 0, 0)
Huang et al. [10]	E: 30; C: 30	CCCD/CCMD/HAMD	E: C:	GV20, GV18, G13 and G9; 30 min, once a day	20 mg/d fluoxetine	30	6	3 (2, 1, 0, 0)
Li et al. [21]	E: 35; C: 35	CCCD/CCMD/HAMD	E: C:	EX-HN1, GV24, G13, LI4, LR3; 30 min, once a day	20 mg/d fluoxetine	28	4	1 (1, 0, 0, 0)
Zhu et al. [22]	E: 32; C: 30	CCCD/CCMD/HAMD	E: C:	LI4, LR3; 20 min, once a day	20 mg/d fluoxetine	40	8	1 (1, 0, 0, 0)
Chen [11]	E: 47; C: 47	CCCD/CCMD/HAMD	E: C:	GV20, EX-HN1, ST8, GB8, HT7; 30 min, once a day	20 mg/d fluoxetine	36	12	3 (2, 1, 0, 0)
Peng et al. [23]	E: 58; C: 59	CCCD/CCMD/HAMD	E: C:	Nie San Zheng, PC6, ST36, LR3, ST40; 20 min, once a day	20 mg/d fluoxetine	24	4	3 (2, 1, 0, 0)
Guo et al. [12]	E: 32; C: 31	CCCD/CCMD/HAMD	E: C:	GV20, EX-HN1, GV24, EX-HN3, LI4, LR3; 30 min, once a day	20 mg/d fluoxetine	30	6	1 (1, 0, 0, 0)
Zhou et al. [13]	E: 145; C:148	CCCD/CCMD/HAMD	E: C:	GV20, EX-HN3, GV24, GV26, LI4, PC6, SP6, ST36, LR3; 30 min, once a day	20 mg/d fluoxetine	45	8	2 (2, 0, 0, 0)
Bi et al. [15]	E: 31; C: 32	CCCD/HAMD	E: C:	GV20, EX-HN3; 45 min, once a day	20 mg/d fluoxetine	30	6	2 (2, 0, 0, 0)
Zhou [14]	E: 32; C: 34	CCCD/HAMD	E: C:	GV20, EX-HN3; 45 min, once a day	20 mg/d fluoxetine	28	4	1 (1, 0, 0, 0)
Dong et al. [24]	E: 74; C: 34	CCCD/CCMD/HAMD	E: C:	GV24, GV17, GB5, GB6, GV18, GB15, GB8, GB7, EX-HN3; 30 min, once a day	20 mg/d fluoxetine	30	4	2 (2, 0, 0, 0)
Chu et al. [16]	E: 36; C: 36	CCCD/CCMD/HAMD	E: C:	GV20, EX-HN3, GV26, PC6; 30 min, once a day	20 mg/d fluoxetine	40	8	2 (2, 0, 0, 0)
Chen et al. [17]	E: 30; C: 30	CCCD/CCMD/HAMD	E: C:	GV20, GV24, EX-HN1, EX-HN3,; HT7, PC6, LR3; 20 min, once a day	20 mg/d fluoxetine	20	4	2 (2, 0, 0, 0)
Long et al. [18]	E: 36; C: 36	CCCD/HAMD	E: C:	GV20, EX-HN3; 45 min, once a day	10-40 mg/d fluoxetine	24	4	1 (1, 0, 0, 0)