Research Article

Mutation Profile Assessed by Next-Generation Sequencing (NGS) of Circulating Tumor DNA (ctDNA) in Chinese Lung Adenocarcinoma Patients: Analysis of Real-World Data

Table 3

Single mutation of EGFR gene.

EGFR gene mutationsNumber of patientsPercentage (%)

Exon-19 del1551.72
Exon-21 L858R1034.48
Exon-19 ins13.45
Exon-20 ins13.45
Exon-21 L861Q13.45
Gene amplification13.45
Total analyzed29100.00

In our cohort, exon-19 (62.16%) was the most common EGFR gene mutation, followed by exon-21 L858R mutation (27.02%).