Research Article
Identification of Multiple Hub Genes and Pathways in Hepatocellular Carcinoma: A Bioinformatics Analysis
Table 1
The detailed information and primer sequences of ten hub genes screened out by PPI networks.
| | Category | Gene abbreviation | Description | Forward primer (5-3) | Reverse primer (5-3) |
| | Upregulated | CDK1 | Cyclin-dependent kinase 1 | CAGGTCAAGTGGTAGCCATG | ACCTGGAATCCTGCATAAGC | | CCNB1 | Cyclin B1 | AAGGCGAAGATCAACATGGC | CCAATGTCCCCAAGAGCTGT | | MAD2L1 | Mitotic arrest deficient 2 like 1 | CGGTGACATTTCTGCCACTG | GGTCCCGACTCTTCCCATTT | | CCNB2 | Cyclin B2 | CTGTACATGTGCGTTGGCAT | CTTGGAAGCCAAGAGCAGAG | | CDC20 | Cell division cycle 20 | CAGCAGAAACGGCTTCGAAA | ACCCGAACATCATGGTGGTG |
| | Downregulated | CYP3A4 | Cytochrome P450 3A4 | TGAAAGAAAGTCGCCTCGAA | CCAGATCGGACAGAGCTTTG | | UGT1A6 | Uridine diphosphate glucuronosyl transferase 1A6 | CCGTGTTCCCTGGAGCATAC | AGGAAGTTGGCCACTCGTTG | | AOX1 | Alcohol oxidase 1 | AATTCCTCAGCAAGTGCCCT | CGGAAGGCTGACACAAATTC | | UGT1A4 | Uridine diphosphate glucuronosyl transferase 1A4 | TGCCATACTTTTTCTGCCCC | AACAGCCACACGGATGCATA | | UGT2B15 | Uridine diphosphate glucuronosyl transferase 2B15 | CTGGAAGCTGTGGAAAGGTG | CACCTCATGACCCCTCTGAA |
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PPI: protein-protein interaction.
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