Long Noncoding RNA FOXP4-AS1 Predicts Unfavourable Prognosis and Regulates Proliferation and Invasion in Hepatocellular Carcinoma

Table 1

Clinicopathological features by FOXP4-AS1 expression levels.

	Training set				Validation set				Combined set
Clinicopathologic parameters	Total ()	Low ()	High ()	value	Total ()	Low ()	High ()	value	Total ()	Low ()	High ()	value
Gender				0.505				0.239				0.978
Female	13	4	9		3	2	1		16	6	10
Male	74	30	44		31	9	22		105	39	66
Age (years)				0.001				0.580				0.001
<60	69	21	48		30	9	21		99	30	69
≥60	18	13	5		4	2	2		22	15	7
Family history				0.142				0.580				0.532
No	79	33	46		30	9	21		109	42	67
Yes	8	1	7		4	2	2		12	3	9
AFP				0.002				0.138				<0.001
<400 ng/ml	43	24	19		12	6	6		55	30	25
≥400 ng/ml	44	10	34		22	5	17		66	15	51
HBVDNA				0.478				1.000				0.422
Negative	22	10	12		8	3	5		30	13	17
Positive	65	24	41		26	8	18		91	32	59
Metastasis				0.142				1.000				0.367
No	79	33	46		29	9	20		108	42	66
Yes	8	1	7		5	2	3		13	3	10
Tumor diameter				<0.001				0.070				<0.001
<5 cm	18	14	4		6	4	2		24	18	6
≥5 cm	69	20	49		28	7	21		97	27	70

AFP: alpha-fetoprotein; HBVDNA: hepatitis B virus-dexoyribonucleic acid.