Intratumoral STING Agonist Injection Combined with Irreversible Electroporation Delays Tumor Growth in a Model of Hepatocarcinoma

Figure 1

Treatment of B16.OVA tumor cells by irreversible electroporation plus c-di-GMP. Mice were challenged s.c. with B16-OVA tumor cells and at days 7-10, when tumors reached 5 mm in diameter, they were treated i.t. as indicated. (a) Each curve represents tumor mean diameter for an individual mouse. Numbers of mice free of tumors out of the total animals per group are indicated. (b) The Kaplan-Meier plots of the percentage of mice survival are represented. Log-rank (Mantel-Cox) test. p < 0.05.

(a)

(b)