GEE-TGDR: A Longitudinal Feature Selection Algorithm and Its Application to lncRNA Expression Profiles for Psoriasis Patients Treated with Immune Therapies

Table 1

Results of psoriasis lncRNA longitudinal data.

	Ave. of MSE (5-fold CVs)	SD of MSE (CVs)	MSE (all data)	Identified lncRNAs (using all data)
				Baseline	Week 1	Week 2	Week 4
AR1	14.456	3.258	2.101	RAMP2-AS1	RAMP2-AS1	RAMP2-AS1	RAMP2-AS1
Unstructured	3.725	0.498	0.793	XIST; RAMP2-AS1; MIR205	LRRC75A-AS1; PAXIP1-AS1 LINC00667 RAMP2-AS1 MIR205	LRRC75A-AS1 TMEM99 LINC01018 PAXIP1-AS1 LINC01139 RAMP2-AS1	TMEM99; LINC01018 PAXIP1-AS1 LINC01139 RAMP2-AS1
Exchangeable	2.758	1.649	0.767	XIST; RAMP2-AS1 MIR205	LRRC75A-AS1 XIST LINC01139 SDHAP2 RAMP2-AS1	TMEM99 LINC01139 RAMP2-AS1	TMEM99; XIST LINC01018 PAXIP1-AS1; LINC01139 RAMP2-AS1
Independent	2.675	1.694	0.760	SNHG5 LINC01139 RAMP2-AS1 MIR205	SNHG5 RAMP2-AS1; MIR205	SNHG5 TMEM99 RAMP2-AS1; MIR205	SNHG5; XIST LINC01018; LINC01139; RAMP2-AS1; MIR205

Only baseline expression values were used. AR1: autoregressive order 1; MSE: mean squared error; SD: standard deviation; CV: crossvalidation.