Elevated Circular RNA PVT1 Promotes Eutopic Endometrial Cell Proliferation and Invasion of Adenomyosis via miR-145/Talin1 Axis

Figure 1

circPVT1 was upregulated in human ADS endometrial tissue and cells. (a) The relative expression of circPVT1 was elevated in adenomyotic eutopic endometrium (ADS_Euc, ) and ectopic endometrium (ADS_Ec, ), as detected by qRT-PCR and normalized against unpaired normal uterine endometrium (Con_En, ). (b) qRT-PCR analysis of circPVT1 in ADS and normal uterine endometrial cells. Four types of primary cells are as follows: Eu_EEC, adenomyotic eutopic endometrial epithelial cell; Eu_ESC, adenomyotic eutopic endometrial stromal cell; Con_EEC, normal uterine endometrial epithelial cell as control; Con_ESC, normal uterine endometrial stromal cell as control. At least triplicate independent experiments were performed. All data were presented as . , , , and ; NS: no significance.

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