A Novel Glucose Metabolism-Related Gene Signature for Overall Survival Prediction in Patients with Glioblastoma

Table 2

Univariable and multivariable analyses for each clinical feature.

Clinical feature	Univariate analysis			Multivariate analysis
	HR	95% CI of HR	value	HR	95% CI of HR	value
Risk score (low-risk/high-risk)	2.357	1.734-3.204	<0.001	1.822	1.252-2.651	0.002
Gender (female/male)	1.332	0.788-2.250	0.284	1.167	0.592-2.299	0.655
Age (<65/≥65)	2.576	1.515-4.379	<0.001	2.270	1.274-4.044	0.005
KPS (<60/≥60)	0.983	0.964-1.002	0.082	0.984	0.960-1.009	0.215
Radiotherapy (untreated/treated)	0.298	0.160-0.555	<0.001	0.348	0.131-0.926	0.035
Chemotherapy (untreated/treated)	0.488	0.267-0.892	0.020	1.468	0.559-3.855	0.436
IDH status (wild/mutant)	0.229	0.056-0.943	0.041	0.583	0.122-2.793	0.499
MGMT promoter status (unmethylated/methylated)	0.539	0.316-0.920	0.023	0.879	0.457-1.689	0.698