Forskolin Protected against Streptozotocin-Induced Diabetic Cardiomyopathy via Inhibition of Oxidative Stress and Cardiac Fibrosis in Mice

<div>Effects of FSK treatment on the expression of cardiac fibrosis-related makers in diabetic hearts. The protein expression of FN, collagen I, TGF-<i>β</i>, and <i>α</i>-SMA was significantly decreased by FSK treatment in a diabetic heart. Representative images of western blot and the corresponding analysis results of FN (a), collagen I (b), TGF-<i>β</i> (c), and <i>α</i>-SMA (d) were shown. 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BioMed Research International

fig5

Figure 5

Figure 5: Forskolin Protected against Streptozotocin-Induced Diabetic Cardiomyopathy via Inhibition of Oxidative Stress and Cardiac Fibrosis in Mice 