Determination of Potential Therapeutic Targets and Prognostic Markers of Ovarian Cancer by Bioinformatics Analysis

Table 1

CXCR mRNA expression difference in ovarian cancer and ovarian tissues (ONCOMINE database).

CXC	Types of ovarian cancer vs. ovarian	value	-test	Fold change	Ref.
CXCR1	Ovarian cancer vs. normal	NA	NA	NA	NA
	Ovarian adenocarcinoma type vs. ovarian endometrioid adenocarcinoma	2.29-5	6.178	2.348	[13]
	Ovarian carcinoma type vs. ovarian adenocarcinoma	8.71-4	5.043	1.825	[11]
CXCR2	Ovarian cancer vs. normal	NA	NA	NA	NA
	Cancer type vs. ovarian cancer	2.69-4	4.050	2.477	[15]
	Ovarian adenocarcinoma type vs. ovarian endometrioid adenocarcinoma	0.020	2.084	1.628	[16]
	Ovarian adenocarcinoma type vs. ovarian mucinous adenocarcinoma	0.014	2.476	2.168	[16]
CXCR3	Ovarian serous surface papillary carcinoma vs. normal	0.014	2.333	1.943	[22]
	Ovarian carcinoma type vs. ovarian adenocarcinoma	0.022	3.157	1.683	[17]
	Cancer type vs. ovarian cancer	0.005	2.853	2.623	[11]
	Cancer type vs. ovarian cancer	0.010	2.416	2.824	[18]
CXCR4	Ovarian serous surface papillary carcinoma vs. normal	2.44-19	22.51	306.41	[15]
	Ovarian serous adenocarcinoma vs. normal	0.012	2.958	3.156	[19]
	Ovarian carcinoma vs. normal	3.05-6	7.594	2.632	[21]
	Ovarian mucinous adenocarcinoma vs. normal	0.018	2.466	1.9	[22]
	Ovarian serous adenocarcinoma vs. normal	0.011	2.632	2.086	[22]
	Ovarian serous adenocarcinoma vs. normal	0.021	2.256	1.818	[23]
	Cancer type vs. ovarian cancer	0.010	2.622	2.403	[24]
	Ovarian adenocarcinoma type vs. ovarian serous adenocarcinoma	0.002	2.977	1.720	[25]
	Cancer type vs. ovarian carcinoma	0.002	3.092	2.041	[26]
	Cancer type vs. ovarian cancer	0.018	2.164	2.340	[27]
	Cancer type vs. ovarian carcinoma	2.94-7	5.484	2.355	[28]
	Cancer type vs. ovarian carcinoma	2.49-6	5.976	2.566	[29]
CXCR5	Ovarian cancer vs. normal	NA	NA	NA	NA
	Cancer type vs. ovarian cancer	NA	NA	NA	NA
CXCR6	Ovarian cancer vs. normal	NA	NA	NA	NA
	Cancer type vs. ovarian cancer	NA	NA	NA	NA
CXCR7	Ovarian serous surface papillary carcinoma vs. normal	0.046	1.751	1.698	[15]
	Ovarian cancer vs. ovarian carcinoma	1.20-6	5.598	2.027	[29]
	Ovarian cancer vs. ovarian carcinoma	2.74-5	4.292	1.937	[28]