A Comprehensive Analysis Identified Hub Genes and Associated Drugs in Alzheimer’s Disease

Table 2

Three best-scoring pathway and process enrichment analysis terms of each MCODE component.

MCODE	Genes	GO	Description
MCODE_1	FPR3; CXCL3; APLNR	R-HSA-375276	Peptide ligand-binding receptors	-6.3
		R-HSA-373076	Class A/1 (rhodopsin-like receptors)	-5.6
		R-HSA-418594	G alpha (i) signaling events	-5.3
MCODE_2	GABRB2; GABRG2; GABRA1	CORUM:7461	GABA-A receptor (GABRA1, GABRB2, and GABRG2)	-12.4
		CORUM:5809	GABA-A receptor (GABRA1, GABRB2, and GABRG2)	-12.4
		GO:0071420	Cellular response to histamine	-10.6