Higher Chondrogenic Potential of Extracellular Vesicles Derived from Mesenchymal Stem Cells Compared to Chondrocytes-EVs In Vitro

Figure 2

Characterization of extracellular vesicles (EVs) derived from chondrocytes (Cho-EVs) and mesenchymal stem cells (MSCs) (MSC-EVs). (a) Scanning electron microscope (SEM) images of Cho-EVs and MSC-EVs. (b) Western blot analysis of specific EV surface marker expression, including CD9 and CD81 and calnexin. (c) Particle size distribution measured by dynamic light scattering (DLS). (d) Uptake of EVs by calcein staining. (e) Western blot analysis of EV proteins, including COL II, ACAN, and COL X. kDa: kilodalton.

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