Construction of miRNA-mRNA-TF Regulatory Network for Diagnosis of Gastric Cancer

Table 1

Screening of differentially expressed genes (DEGs).

	Genes
Downregulated	IGF2BP3 COL1A1 CCNE1 FNDC1 S100A3 COL5A2 THY1 MARVELD3 SPP1 OLR1 ITGA2 TIMP1 BGN COL8A1 CDCA5 CKS2 TEAD4 MMP11 CDH3 MMP3 CRABP2 KRT80 FSCN1 LRP8 LIPG BMP1 PLA2G7 MFAP2 TFAP2A COL4A1 TGIF1 SULF1 IL32 LAMC2 RARRES1 CLDN1 IGSF6 HAVCR2 APOC1 GINS2 COL12A1 ESM1 PLAU SERPINB5 TGM2 FOXC1 FZD2 CST1 CLDN7 NDUFA4L2 HOXA10 ETV4 IER5L CAMK2N1 TNFRSF12A ISG15 ANGPT2 TMEM158 IFITM3 SERPINH1 FAP GJB2 THBS2 S100A10 SERPINE1 MSLN LY6E UPP1 COL6A3 COL10A1 F12 COL5A1 PMEPA1 HOXC6 CTHRC1 FJX1
Upregulated	EPB41L4B COL4A5 ISL1 GHR MAOA ZNF385B PRDM16 KIAA1324 GKN1 GHRL CELA3A APOBEC2 SULT1C2 FCGBP GPRC5C KCNJ13 AKR7A3 IRX3 DGKD SORBS2 KLF4 MT1G CYP3A5 GC ALDH6A1 C5 VSIG1 PDGFD FAM3B KIT NTN4 TNFRSF17 CA9 SH3BGRL2 CBS ADH1C NPY IGFBP2 PIK3C2G SLC9A2 GCNT2 SST PLCXD3 ECHDC3 XYLT2 TPD52L1 ZBTB7C GGT6 PDK4 CXCL17 LYPD6B NR3C2 PDIA2 SLC22A23 TCEAL2 MT1E ANXA10 CA4 ADHFE1 ADAM28 MUC6 OSBPL7 KRT20 HRASLS2 CTSE GIF ABCC5 RNASE1 MT1F SOSTDC1 ACACB RORC PNPLA7 VSIG2 FAM46C CHRM3 TMED6 SH3GL2 SCNN1G CKMT2 PSCA KCNJ16 REG3A TFF1 RPRM CYFIP2 FAM3D CKM FBXL13 RNASE4 ST6GALNAC1 DERL3 PTGER3 COBLL1 DNASE1 CXCL14 LDHD PROM2 FBP2 AKR1B10 SOX21 ARL14 AADAC GSTA4 ATP4A POU2AF1 UGT2B15 CKB CD36 LRRC17 RAP1GAP IGFALS TSC22D3 PIGR CDH2 MAL AQP4 CHGA RAB26 MT1M ESRRG APLP1 VILL TMEM171 CPA2 ABCA8 RAB27B FA2H ADH7 PDILT AMPD1 SULT2A1 GAMT TFF2 CCKBR HPGD RBPMS2 ARRDC4 SCGB2A1 SLC7A8 ADA TMPRSS2 DUOX1 LIPF DPT GUCA2B CYP4X1 CAPN13 TCN1 EPN3 SLC2A12 SORBS1 ENPP5 LIFR NQO1 CD79A CYB5R1 CYP2C18 FGA ALDH3A1 FUT9 PTGR1 AZGP1 ALDH1A1 FMO5 IRX2 CA2 LTF GATA5 ATP4B BCAS1 SIDT2 SLC26A9 ADH1A CHIA METTL7A FAM189A2 SSTR1 PGC MYRIP FABP4 KCNE2 FAM107A GPX3 PPP1R3C MT1H SIGLEC11 PTGS1 ALDOB KLK11 DNER MAMDC2 C1orf116 CLDN18 HDC RASSF6 SELENBP1 CLIC6 TRIM50