Ginsenoside CK Inhibits TGF-β-Induced Epithelial-Mesenchymal Transition in A549 Cell via SIRT1

Figure 1

Effect of ginsenoside CK on TGF-β-induced EMT in A549 cells. (a) A549 cells were treated with TGF-β, with or without 1.5 μg·mL^-1 or 3 μg·mL^-1 ginsenoside CK for 24 h, and the protein expression of vimentin and E-cadherin was determined by Western blotting (a) and immunofluorescence staining (b). (c) The mRNA levels of EMT-related transcription factors, including Snail, Slug, and Zeb1, were measured using qRT-PCR. All scale bars represent 50 μm. Error bar, SD of three independent experiments. .

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