Ginsenoside CK Inhibits TGF-β-Induced Epithelial-Mesenchymal Transition in A549 Cell via SIRT1

Figure 6

Effect of SIRT1 overexpression on the migration and invasion abilities of A549 cells with ginsenoside CK pretreatment. Cells were transfected with SIRT1 plasmid and then further incubated in the presence of ginsenoside CK for 24 h. Wound healing assay and Transwell assays assessed tumor cell migration capacity in A549 cells. The mRNA levels of Snail, Slug, and Zeb1 were measured by RT-PCR. .

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