Differential Expression Profiles and Functional Prediction of circRNAs in Necrotizing Enterocolitis

Figure 2

Identification of differentially expressed circRNAs in the NEC model. (a) Scatter plot of differentially expressed circRNAs. (b) Heatmap of differentially expressed miRNAs. (c) The number of circRNAs generated by host genes. Some linear genes produce only one circularized RNA, whereas some linear genes produce multiple circularized RNAs. The abscissa indicates the number of circRNAs produced by linear RNAs, whereas the ordinate is the corresponding number of linear RNAs. (d) Distribution of circRNAs in the chromosome. SRPBM: spliced reads per billion mapped.

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