Research Article

Abrus precatorius Leaf Extract Reverses Alloxan/Nicotinamide-Induced Diabetes Mellitus in Rats through Hormonal (Insulin, GLP-1, and Glucagon) and Enzymatic (α-Amylase/α-Glucosidase) Modulation

Table 1

Effect of APLE on organ weight/bodyweight ratios and bodyweight change.

Organ weight/body weight ratioBody weight (g)
SpleenLiverKidneyPancreasInitialFinal% change in body weight

Control0.58
Model-6.57a
Metformin (mg/kg)-0.02ns
APLE (mg/kg)
1005.10b
200-3.86ns
400-0.99ns

Received normal saline; APLE: Abrus precatorius leaf extract (APLE); ns: not significant; a (model vs. control); b (APLE and metformin vs. model).