Abrus precatorius Leaf Extract Reverses Alloxan/Nicotinamide-Induced Diabetes Mellitus in Rats through Hormonal (Insulin, GLP-1, and Glucagon) and Enzymatic (α-Amylase/α-Glucosidase) Modulation

Table 2

Effect of APLE on elevated blood glucose levels of Alloxan/nicotinamide-induced diabetic rats.

Treatment groups	Day of blood glucose peak	Blood glucose level after Alloxan/nicotinamide exposure (mmol/L)	Blood glucose level on day 18 (mmol/L)	Mean decrease in blood glucose	% decrease in blood glucose
Control	9				11.96
Model	12				4.34^a
Metformin (300 mg/kg)	12				43.63^b
APLE (mg/kg)
100	9				68.67^b
200	12				31.07^b
400	15				4.39^ns

Received normal saline; ^a (model vs. control); ^b (APLE and metformin vs. model); APLE: Abrusprecatorius leaf extract; ns: not significant.