Abrus precatorius Leaf Extract Reverses Alloxan/Nicotinamide-Induced Diabetes Mellitus in Rats through Hormonal (Insulin, GLP-1, and Glucagon) and Enzymatic (α-Amylase/α-Glucosidase) Modulation

Table 5

Estimated IC₅₀ values for APLE and standards.

	Drugs and standards	IC50 (μg/mL)
FRAC	APLE	2.799
	Quercetin	3.243
DPPH radical scavenging activity	APLE	115.100
	Ascorbic acid	107.900
NO radical scavenging activity	APLE	1100.000
	Gallic acid	1670.000
	Ascorbic acid	1236.000
α-Glucosidase enzymatic activity	APLE	1090.000
	Acarbose	1176.000
α-Amylase enzymatic activity	APLE	297.000
	Acarbose	259.100

Values represent EC₅₀; APLE: Abrus precatorius leaf extract; DPPH: 2, 2,-diphenyl-1-picrylhydrazyl; FRAC: ferric reducing antioxidant capacity; NO: nitric oxide.