Research Article

Association of Low High-Density Lipoprotein Cholesterol Levels with Poor Outcomes in Hepatitis B-Associated Decompensated Cirrhosis Patients

Table 1

Patient characteristics at baseline.

All patients ()Surviving patients ()Nonsurviving patients ()

Gender (female/male)30/12322/1028/210.346
Age (years)53.0 (46.0-63.0)53.0 (46.0-63.0)55.0 (47.8-61.5)0.952
Total protein (g/L)61.5 (56.5-66.8)61.7 (57.8-67.2)59.4 (52.4-65.9)0.098
Albumin (g/L)30.6 (26.4-34.6)31.4 (27.4-35.1)28.9 (23.7-31.2)0.011
Alanine aminotransferase (U/L)29.0 (16.0-43.0)28.0 (15.5-39.0)38.0 (22.3-57.0)0.102
Aspartate aminotransferase (U/L)42.0 (27.8-71.0)40.5 (27.0-63.5)54.0 (31.8-97.5)0.038
Serum creatinine (μmol/L)74.0 (61.0-87.0)73.5 (61.0-84.0)92.0 (61.8-124.0)0.065
Total bilirubin (μmol/L)36.0 (17.8-83.3)31.5 (16.0-59.0)117.0 (64.8-212.5)<0.001
Blood urea nitrogen (μmol/L)5.8 (4.3-7.7)5.5 (4.2-7.4)7.2 (5.8-12.9)0.002
INR1.34 (1.18-1.61)1.30 (1.16-1.51)1.67 (1.50-1.90)<0.001
HDL-C (mmol/L)0.73 (0.45-1.07)0.82 (0.57-1.20)0.40 (0.16-0.62)<0.001
Platelet (×109/L)66.0 (40.8-120.3)65.5 (39.5-113.0)72.0 (59.3-159.3)0.208
Hemoglobin (g/L)101.0 (84.0-117.3)103.5 (83.5-118.0)94.0 (87.5-113.3)0.407
MELD score11.4 (6.8-16.8)9.9 (6.0-13.7)19.7 (15.4-22.5)<0.001

Data are expressed as number or median (interquartile range). Abbreviations: INR: international normalized ratio; HDL-C: high-density lipoprotein cholesterol; MELD: Model for End-stage Liver Disease.