Toxic Effect of Khat in Rat Embryos and Fetuses

Table 7

Comparison of histopathological alterations in rat placenta.

Group	Percent of placental abnormalities
	Decidual necrosis	Cytolysis	Necrosis	Apoptosis	Severe decidual hypoplasia/atrophy
Control	0	0	0	0	0
K250	25	25	0	0	0
K500	50	100^a	0	25	0
K750	50	50	25	50	25
Ad libitum control	0	0	0	0	0

K250: khat extract 250 mg/kg; K500: khat extract 500 mg/kg; K750: khat extract 250 mg/kg; results are summarized as percentages of placental abnormalities; ^asignificant difference seen from the ad libitum and pair-fed control groups (), chi-square.