Role of PI3K/AKT Signaling Pathway in Nucleus Pulposus Cells

Figure 3

(a–f) Western blot showing that PI3K/AKT inhibitor LY294002 downregulated the ratio of p-AKT to t-AKT and the protein expression of Col-II and aggrecan as well as upregulated the protein expression of MMP13 and Col-X in NP cells. Protein expression was normalized to β-actin. (, , , ).

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