miR-101-3p Serves as a Tumor Suppressor for Renal Cell Carcinoma and Inhibits Its Invasion and Metastasis by Targeting EZH2

Figure 4

Overexpressing miR-101-3p prevented RCC proliferation in vivo. (a, b) The expression of EZH2 in A498 cell lines was measured by Western blotting and qRT-PCR. (c, d) Weights of the xenografts were shown in the box plot (). Macroscopic appearance of the tumors in nude mice from the 8-week-old groups. (f) Tumor volumes were periodically measured for each mouse, and tumor growth curves were plotted. Data represent . (g) Representative IHC staining of EZH2 from the indicated tumors (200x, 400x). (h) Tumor incidence and weights of the xenografts were shown in the table () () (, ).

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