Research Article

Development and Validation of a UPLC-MS/MS Method for the Quantitative Determination and Pharmacokinetic Analysis of Cirsimarin in Rat Plasma

Table 1

Accuracy, precision, matrix effect, and recovery of cirsimarin in rat plasma (n =6).

Concentration (ng/mL)Accuracy (%)Precision (RSD %)Matrix effect (%)Recovery (%)
IntradayInterdayIntradayInterday

192.5107.310.513.6104.792.8
4101.899.43.46.9106.684.2
180105.2103.94.57.3107.495.3
2500101.097.18.42.7103.698.0