Research Article

Development and Validation of a UPLC-MS/MS Method for the Quantitative Determination and Pharmacokinetic Analysis of Cirsimarin in Rat Plasma

Table 3

Main pharmacokinetic parameters of cirsimarin in rats.

ParametersUnitIV (1 mg/kg)

AUC(0-t)ng/mL·h
AUC(0-∞)ng/mL·h
MRT(0-t)h
MRT(0-∞)h
h
CLzL/h/kg
VzL/kg
ng/mL