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BioMed Research International
/
2021
/
Article
/
Tab 3
/
Research Article
Development and Validation of a UPLC-MS/MS Method for the Quantitative Determination and Pharmacokinetic Analysis of Cirsimarin in Rat Plasma
Table 3
Main pharmacokinetic parameters of cirsimarin in rats.
Parameters
Unit
IV (1 mg/kg)
AUC
(0-
t
)
ng/mL·h
AUC
(0-∞)
ng/mL·h
MRT
(0-
t
)
h
MRT
(0-∞)
h
h
CLz
L/h/kg
Vz
L/kg
ng/mL