Levels of C-Reactive Protein and Sodium May Differentiate a Perforated Appendix from a Nonperforated Appendix in Children

Table 2

Analyses of ROC curves for selected variables.

	AUC (±SE)	Cutoff	Sensitivity	Specificity	95% CI		PPV	NPV	OR (95% CI)
Age ()		6,5	52%	84%	0.66–0.79	<0.001	49%	86%	5.9 (3.3–10.6)
Temperature (°C)		38.0	68%	75%	0.68–0.82	<0.001	46%	88%	6.1 (3.3–11.6)
Tzanakis score		12.5	49%	91%	0.63–0.77	<0.001	63%	86%	10.0 (5.2–19.2)
CRP (mg/dL)		4.1	86%	79%	0.83–0.93	<0.001	55%	95%	22.5 (10.7–47.2)
CLR (mg/dL/10^9/L)		1.9	97%	72%	0.82–0.96	<0.001	42%	94%	27.0 (7.7–95.1)
WBC (10^9/L)		13.4	79%	59%	0.65–0.80	<0.001	38%	95%	12.4 (5.4–28.2)
Sodium (mmol/L)		137.5	69%	80%	0.72–0.86	<0.001	61%	85%	8.7 (4.2–18.0)

AUC: area under the curve; SE: standard error; PPV: positive predictive value; NPV: negative predictive value; OR: odds ratio; CI: confidence interval; CRP: C-reactive protein; WBC: white blood cell. CLR: C-reactive protein-to-lymphocyte ratio.