Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs

Figure 1

Effect of curcumin on HUVEC viability after PA treatment. (a). Dose-dependent effect of PA (25 μM, 50 μM, 100 μM, and 200 μM) on HUVEC viability after 24 h (; 1-way ANOVA with Dunnett’s test). (b). Effect of curcumin (1.25 μM, 2.5 μM, and 5 μM) on HUVEC viability after 24 h (; 1-way ANOVA with Dunnett’s test). (c). HUVECs were exposed to PA (100 μM) with or without pretreatment (30 min) with curcumin (2.5 μM) for 24 h, and cell viability was measured using the CCK-8 assay (; 1-way ANOVA with Duncan’s posthoc test). The data are shown as (, vs. the Cont group; ^# vs. the PA group).

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