Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs

Figure 5

Curcumin inhibits PA-induced LOX-1 upregulation. (a) The protein expression level of LOX-1 was measured by Western blotting. (b) The expression was quantified via densitometry using ImageJ software (; 1-way ANOVA with Duncan’s posthoc test). (c) The protein expression levels of Bip, CHOP, and LOX-1 were measured by Western blotting. The expression of LOX-1 (d) was quantified via densitometry using ImageJ software (; 1-way ANOVA with Duncan’s posthoc test). (e) The mRNA expression level of LOX-1 was measured via quantitative PCR (; 1-way ANOVA with Duncan’s posthoc test). (f) Images of immunofluorescence staining of LOX-1 in HUVECs in different groups. The data are shown as (, vs. the Cont group;^# vs. the PA group).

(a)

(b)

(c)

(d)

(e)

(f)