Molecular Docking, Synthesis, and Tyrosinase Inhibition Activity of Acetophenone Amide: Potential Inhibitor of Melanogenesis

Figure 1

Structural components of representative compound 2-(3-acetylphenylamino)-2-oxoethyl(E)-3-(2,4-dihydroxyphenyl)acrylate (5c) responsible for its enhanced tyrosinase inhibition.