Molecular Docking, Synthesis, and Tyrosinase Inhibition Activity of Acetophenone Amide: Potential Inhibitor of Melanogenesis

Figure 4

Ball and stick illustration of the docking pose of (a) Kojic acid (green), (b) 2D ligand interaction diagram, (c) surface and stick representation (purple), and (d) ball and stick representation of 2-(3-acetylphenylamino)-2-oxoethyl(E)-3-(2,4-dihydroxyphenyl)acrylate (5c), (blue) in the binding pocket of tyrosinase 2Y9X. The 5c is binding closer to Cu²⁺(brown) in the active site.

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