Molecular Docking, Synthesis, and Tyrosinase Inhibition Activity of Acetophenone Amide: Potential Inhibitor of Melanogenesis

<div>Synthetic pathway for title derivatives 3(a–e); reaction conditions and reagents; (i) dichloromethane (CH<sub>2</sub>Cl<sub>2</sub>)/triethylamine (C<sub>2</sub>H<sub>5</sub>)<sub>3</sub>N, 0-5°C, 5 hours stirring (ii) dimethylformamide (DMF)/(C<sub>2</sub>H<sub>5</sub>)<sub>3</sub>N/KI, stirring for 24 hours at room temperature.</div>

BioMed Research International

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Scheme 1

Scheme 1: Molecular Docking, Synthesis, and Tyrosinase Inhibition Activity of Acetophenone Amide: Potential Inhibitor of Melanogenesis 