Comparison between Clinical Utility of CXCL-8 and Clinical Practice Tumor Markers for Colorectal Cancer Diagnosis

Table 1

Statistical values of CXCL-8, CEA, and CA19-9 alone and combined for the differential diagnosis between patients with colorectal cancer and healthy participants.

Variable	AUC	Accuracy (%)	Cut-off value	Sensitivity (%)	Specificity (%)	95% Confidence interval
						Lower limit	Upper limit
CXCL-8	0.920	84.57	24.92	86.34	81.30	89.24	94.80
CEA	0.837	57.43	5	34.80	99.19	75.59	87.88
CA19-9	0.730	45.43	37	15.86	100	67.81	78.26
CXCL-8 + CEA	0.954	85.14		78.41	97.56	93.51	97.22
CXCL-8 + CA19-9	0.940	84.86		82.82	88.62	91.62	96.26
CEA + CA19-9	0.844	77.43		74.45	82.93	80.34	88.41