Comparison between Clinical Utility of CXCL-8 and Clinical Practice Tumor Markers for Colorectal Cancer Diagnosis

Table 2

Statistical values of CXCL-8, CEA, and CA19-9 alone and together for the differential diagnosis between patients with colorectal cancer and patients with colorectal adenoma.

Variable	AUC	Accuracy (%)	Cut-off value	Sensitivity (%)	Specificity (%)	95% Confidence interval
						Lower limit	Upper limit
CXCL-8	0.774	77.15	24.92	86.34	58.18	71.51	83.35
CEA	0.760	54.89	5	34.80	96.36	70.82	81.04
CA19-9	0.686	42.43	37	15.86	97.27	62.67	74.49
CXCL-8 + CEA	0.804	73.59		74.01	72.73	75.71	85.10
CXCL-8 + CA19-9	0.768	73.88		77.53	66.36	71.36	82.19
CEA + CA19-9	0.767	72.41		71.81	73.64	71.67	81.70