Research Article
[Retracted] In Vitro Evaluation of Cytotoxic Potential of Caladium lindenii Extracts on Human Hepatocarcinoma HepG2 and Normal HEK293T Cell Lines
Figure 3
The growth rate of cells was calculated by the crystal violet staining protocol. Optical density (OD) at 570 nm was measured and plotted to obtain the percentage viability of untreated, treated, and control cells. In cell viability assay, a drug response is driven by cell density. A trend-line slope showed the number of cells/well certified to be significant. (a) The calculated percentage elaborated a clear dose-dependent decrease in HepG2 cells with significant R2 (coefficient of determination) values. (b) HEK293T plotted slope remained constant with a slight fall and showed good viability. (c) Hexane extract showed 59% and 50% viability on HepG2 cells at higher (200 and 400 μg/mL) concentrations. (d) Nontumor cells did not show the activity of hexane extract at any concentration. Statistical analysis described as , , and . DMSO: Dimethyl sulfoxide; SD: standard deviation; CV: crystal violet; MTT: 3-(4, 5-dimethylthiazol-2yl)-2, 5-biphenyl tetrazolium bromide.
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