Research Article
[Retracted] In Vitro Evaluation of Cytotoxic Potential of Caladium lindenii Extracts on Human Hepatocarcinoma HepG2 and Normal HEK293T Cell Lines
Figure 4
The morphological features showed the effect of hexane extract of C. lindenii on both HepG2 and HEK293T cells. (a) In vitro treatment of hexane extract on HepG2 cells demonstrated mild alteration in cell morphology at all concentrations except the higher (200 and 400 μg/mL) concentrations. The lower concentrations 10, 50, and 100 μg/mL did not show satisfactory results. Cells treated with high concentrations became degraded and shrunken. 50% of cell reduction was calculated by percentage viability assay at 400 μg/mL. (b) The nontumor HEK293T cells showed normal morphology at all concentrations and did not reveal any sign of toxicity in comparison with UT and DMSO (negative control). Cisplatin (10 μg/mL) was the positive control applied on healthy (HEK293T) as well as cancer (HepG2) cells showed 45% and 42% of cell viability, respectively.
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